FLAVOXATE HYDROCHLORIDE

Synonyms. Flavoxate hydrochloride; 3-Methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carboxylic acid 2-(1-piperidinyl)ethyl ester hydrochloride; 2-Piperidinoethyl 3-methyl-4-oxo-2-phenyl-4H-1-benzopyran- 8-carboxylate hydrochloride; Bladderon; Peflate; Piperidinoethyl-3-methylflavone-8-carboxylate hydrochloride;

FLAVOXATE

Click for original image

 

PRODUCT IDENTIFICATION

CAS RN

3717-88-2

EINECS RN

223-066-4

FORMULA

C24H25NO4·HCl

MOLE WEIGHT

427.92

H.S CODE

2934.99.4400

SMILES

c12c(c(c(C)c(o2)c2ccccc2)=O)cccc1C(OCCC1CC[NH2+]CC1)=O.[ClH-]

CLASSIFICATION

Flavone, Relaxant, Antispasmodic, Antimuscarinic

EXTRA NOTES

A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. (MeSH)

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE.

light yellow power

MELTING POINT

232 ~ 234 C

BOILING POINT

 

DENSITY

 

SOLUBILITY IN WATER

Practically insoluble

SOLVENT SOLUBILITY

 

VAPOR DENSITY

 

log P(octanol-water)

 

VAPOR PRESSURE

 

AUTOIGNITION TEMP

 
pH

 

REFRACTIVE INDEX

 

FLASH POINT

 

 

STABILITY AND REACTIVITY
STABILITY Stable under normal conditions.

INCOMPATIBLE MATERIALS

Oxidizing agents

POLYMERIZATION

Has not been reported

NFPA RATINGS

Health: 2, Flammability:0, Reactivity: 0

 

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Flavoxate

Google Scholar Search - Flavoxate

Drug Information Portal (U.S. National Library of Medicine) - Flavoxate

PubChem Compound Summary - Flavoxate

Drug Bank -  Flavoxate

KEGG (Kyoto Encyclopedia of Genes and Genomes) - Flavoxate

http://www.ebi.ac.uk/ - Flavoxate

http://www.ncbi.nlm.nih.gov/ - Flavoxate

 

SALES SPECIFICATION

APPEARANCE

light yellow power

CONTENT

98.0% min

LOSS ON DRYING

1.0% max

HEAVY METALS

20ppm max

MELTING POINT

> 300 C

 

TRANSPORT & REGULATORY INFORMATION

UN NO.

Not regulated

HAZARD CLASS

 
PACKING GROUP  

 

SAFETY INFORMATION

HAZARD OVERVIEW

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

GHS

 

SIGNAL WORD

Warning

PICTOGRAMS

HAZARD STATEMENTS

H302-H315-H319-H335

P STATEMENTS

P261-P305 + P351 + P338

EC DIRECTIVES

 

HAZARD CODES

Xn

RISK PHRASES

22-36/37/38

SAFETY PHRASES

26

 

PACKING

Preserve in light-resistant and well-closed containers